抗病毒药物溴夫定

摘要/Abstract

摘要：

带状疱疹属于病毒感染性皮肤病，ZAP和PHN是其主要的并发症，尤其容易发生在50岁以上的患者。早期、足量、规范系统抗病毒药物治疗能明显缩短带状疱疹的治愈时间，降低PHN的发生。溴夫定是一种核苷类似物，具有高效和高选择性抗VZV，其抗病毒活性明显优于阿昔洛韦及其衍生物。溴夫定125mg，每天1次，疗程7天治疗带状疱疹与阿昔洛韦和泛昔洛韦一样有效安全，但在预防PHN发生方面明显优于阿昔洛韦，且每天1次的用药方法明显提高了患者的依从性，降低了服药的风险性，无疑是带状疱疹治疗的最佳选择之一。但需谨记本品不得与氟尿嘧啶或类似的抗癌药物联合应用。

关键词: 溴夫定, 带状疱疹, 药物相互作用

Key words: Brivudine, herpes zoster, drug-drug interaction

王爱平王军李若瑜. 抗病毒药物溴夫定[J]. 中华皮肤科杂志, 2010, 43(8): 595-597.

参考文献

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