中华皮肤科杂志 ›› 2004, Vol. 37 ›› Issue (2): 97-99.

• 论著 • 上一篇    下一篇

西安、重庆两所医院20年皮肤恶性黑素瘤回顾

孙东杰1, 高天文1, 李春英1, 刘荣卿3, 李青2, 刘友生4, 刁庆春3, 何弘1, 黄高升2, 郝飞3, 马福成2, 柳凤轩4, 钟白玉3, 闫小初4, 刘东梅4, 李廷慧1, 刘玉峰1   

  1. 1. 第四军医大学西京医院全军皮肤性病中心 西安 710032;
    2. 第四军医大学西京医院病理科 西安 710032;
    3. 第三军医大学西南医院皮肤科 西安 710032;
    4. 第三军医大学西南医院病理科 西安 710032
  • 收稿日期:2003-03-27 出版日期:2004-02-15 发布日期:2004-02-15
  • 通讯作者: 高天文,E-mail:gaotw@fmmu.edu.cn E-mail:gaotw@fmmu.edu.cn

Review of Cutaneous Malignant Melanoma from Two General Hospitals in Western China, 1981-2000

SUN Dong-jie1, GAO Tian-wen1, LI Chun-ying1, LIU Rong-qing3, LI Qing2, LIU You-sheng4, DIAO Qing-chun3, HE Hong1, HUANG Gao-sheng2, HAO Fei3, MA Fu-cheng2, LIU Feng-xuan4, ZHONG Bai-yu3, YAN Xiao-chu4, LIU Dong-mei4, LI Ting-hui1, LIU Yu-feng1   

  1. Department of Dermatology of Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China
  • Received:2003-03-27 Online:2004-02-15 Published:2004-02-15

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摘要： 目的 了解西安及重庆两所医院20年来皮肤恶性黑素瘤的临床、病理特点及发病趋势;比较两地差异;探讨皮肤恶性黑素瘤发病诱因。方法 收集1981年1月1日至2000年12月31日新确诊的305例患者的临床资料,并对185例具备完整病理资料者进行分析。结果 63.3%的皮肤恶性黑素瘤发生于肢端;依据临床病史,15.8%原发部位曾有先天性小痣;20世纪80、90年代皮肤恶性黑素瘤分别占同期病理活检数比例为0.053%、0.094%,该比例的年增长率为3.9%;20年来面、颈部皮肤恶性黑素瘤比例逐渐增加,足部减少。结论 肢端是皮肤恶性黑素瘤最常见的发病部位,20年来上述两所医院皮肤恶性黑素瘤占活检数的比例有增加的趋势。

关键词: 黑色素瘤, 痣

Abstract: Objective To review the clinical-pathological features, the tendency of incidence over 20 years, the predisposing factors, and the differences between the cases of cutaneous malignant melanoma from two hospitals. Methods A collection of 305 cases diagnosed as cutaneous malignant melanoma, among which 185 cases had complete clinical-pathological data, during 1981-2000 was analyzed. Results Acral malignant melanoma accounted for 63.3%, and the cases associated with congenital small nevi at the primary site accounted for 15.8% of 305 patients. During the period 1981-1990 and 1991-2000, cutaneous malignant melanoma constituted 0.053% and 0.094%, respectively, of all diagnoses with pathological sections, with an growth rate of 3.9% yearly. There was a tendency of the increased lesions located on face and neck, and decreased lesions on acra, over 20 years. Conclusion A rise of diagnosis of cutaneous malignant melanoma has been noticed from two hospitals over 20 years. Acra, especially planta, is the predominant anatomical site of cutaneous malignant melanoma.

Key words: Melanoma, Nevus