中华皮肤科杂志 ›› 1996, Vol. 29 ›› Issue (6): 415-417.

• 论著 • 上一篇    下一篇

向血管性T细胞淋巴瘤

陈明华1, 邱丙森1, 孔今城2, 陈建中3   

  1. 1. 上海医科大学皮肤病学研究所 200040 ;
    2. 上海市第一人民医院病理科;
    3. 解放军第九八医院
  • 收稿日期:1995-10-04 修回日期:1996-01-23 出版日期:1996-12-15 发布日期:1996-12-15
  • 基金资助:
    国家自然科学基金

Angiotropic T-cell Lymphoma

Chen Minghua1, Qiu Bingsen1, Kong Jincheng2   

  1. Institute of Dermatology, Shanghai Medical University, Shanghai 200040
  • Received:1995-10-04 Revised:1996-01-23 Online:1996-12-15 Published:1996-12-15

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摘要： 报告3例罕见的向血管性淋巴瘤,初发症状为皮肤结节和(或)紫癜伴发热,2例血清乳酸脱氢酶和碱性磷酸酶增高.组织病理示真皮和皮下组织内瘤细胞簇集于小血管内,浸润并破坏部分或全部管壁及其周围组织.瘤细胞对白细胞共同抗原和UCHL-1呈阳性反应,提示为T细胞来源.本病预后差,但早期诊断和治疗可延长患者存活期.经中国生物医学文献光盘数据库检索1983年至1995年11月文献,本例为国内首次报道.

关键词: 淋巴瘤.向血管性, T-淋巴细胞

Abstract: Three rare cases of angiotropic lymphoma were reported with a review of literature.The early clinical manifestations were skin nodules and/or purpura associated with fever and the elevation of LDH and AKP.Histopathological examination show ed that multifocal proliferation of neoplastic mononuclear cells infiltrated into the lumina of small blood vessels and resulted in the destruction of the vascular walls and surrounding structures.Immunohistochemical study confirmed its T-celorigin.The prognosis of the diseaseis poor but the patient's survival time can be prolonged with early diagnosis and proper treatment.This is the first report of such disease in our country.

Key words: Lymphoma, angiotropic, Tlymphocytes