中华皮肤科杂志 ›› 1993, Vol. 26 ›› Issue (3): 163-164.

• 论著 • 上一篇    下一篇

乳房外Paget病伴内脏转移

赵德明1, 王平1, 黄福林2   

  1. 1. 南京铁道医学院附属医院皮肤科, 210009;
    2. 南京军区总医院电价室
  • 收稿日期:1992-04-07 修回日期:1992-07-06 出版日期:1993-06-15 发布日期:1993-06-15

Cxtramammary Paget’s disease with metastasis to viscera：A case report

ZHAO De-Ming1, WANG Pin1   

  1. The Affiliated Hospital, Nanjing Railway Medical College, Nanjing 210009
  • Received:1992-04-07 Revised:1992-07-06 Online:1993-06-15 Published:1993-06-15

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摘要： 报道1例乳房外Paget病伴内脏转移.男性,69岁.在右侧肛门边缘发生进行性扩展的皮肤斑块已8年,近1年皮损发展至肛门内.手术治疗中见皮担为连续性伸展至肛肠部形成肿瘤,组织病理学及粘蛋白染色枪查表明肛门部皮损和肛肠部的肿瘤细胞为一致性,即为Paget细胞组成,电镜观察本例的Paget细胞具有腺细胞的特征,表明系乳房外Paget病扩展至肛肠部.

关键词: Paget病, 乳腺外

Abstract: A 89-year-old male patient developed a plaque an the right margin of the anus for 8 years, then gradually spread to the anal canal 1 year age. During operation the skin lesion was observed to have extended to the anal canal and the rectum. Histopatholagical exarninatian showed the same kind of carcinoma cells, i.e.,Paget's cells in the anal canal tumor as well as the skin lesion. Electron microscopic study of the Paget's cells of the anal margin showed features of glandular celis. The clipical manifestations, histoiogic changes, and use of mucin stain suggest that this is a continuous process, an extension of the extramammary Paget's disease from the akin into the anai canal and rectum.

Key words: Paget’s disease, extramammary