中华皮肤科杂志 ›› 2024, e20230448.doi: 10.35541/cjd.20230448
• 综述 • 上一篇
朱婷婷 张学军
收稿日期:2023-08-03
修回日期:2023-11-02
发布日期:2024-02-06
通讯作者:
张学军
E-mail:ayzxj@vip.sina.com
Zhu Tingting, Zhang Xuejun
Received:2023-08-03
Revised:2023-11-02
Published:2024-02-06
Contact:
Zhang Xuejun
E-mail:ayzxj@vip.sina.com
摘要： 【摘要】 银屑病是多种免疫细胞介导的慢性、炎症性、系统性疾病。阿普米司特是一种口服小分子磷酸二酯酶（PDE4）抑制剂，抑制细胞内的PDE4活性，间接提高细胞内环磷酸腺苷水平，平衡促炎因子和抗炎因子的表达，从而恢复自身免疫的稳态，达到治疗银屑病的目的。本文综述阿普米司特治疗斑块状银屑病的有效性、在特殊人群中的应用以及安全性。
朱婷婷 张学军. 阿普米司特在斑块状银屑病治疗中的研究进展[J]. 中华皮肤科杂志, 2024,e20230448. doi:10.35541/cjd.20230448
Zhu Tingting, Zhang Xuejun. Apremilast in the treatment of plaque psoriasis[J]. Chinese Journal of Dermatology,2024,e20230448. doi:10.35541/cjd.20230448
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