中华皮肤科杂志 ›› 2022, Vol. 55 ›› Issue (7): 571-575.doi: 10.35541/cjd.20220016

• 论著 • 上一篇    下一篇

浙江省2011—2020年生殖器疱疹流行特征与趋势分析

曾凡荣    沈云良    杜娜    吴李梅    费丽娟    王燕敏   

  1. 浙江省皮肤病防治研究所，德清  313200
  • 收稿日期:2022-01-07 修回日期:2022-04-28 发布日期:2022-07-05
  • 通讯作者: 沈云良 E-mail:372384823@qq.com
  • 基金资助:
    浙江省基础公益研究计划项目（LGF22H260008、LGF20H260004）；浙江省皮肤病防治研究所医药卫生科技项目（2021YJKT03、2020YJKT07、2018YJKT01）

Epidemiological features and trends of genital herpes in Zhejiang province from 2011 to 2020

Zeng Fanrong, Shen Yunliang, Du Na, Wu Limei, Fei Lijuan, Wang Yanmin   

  1. Zhejiang Provincial Institute of Dermatology, Deqing 313200, Zhejiang, China
  • Received:2022-01-07 Revised:2022-04-28 Published:2022-07-05
  • Contact: Shen Yunliang E-mail:372384823@qq.com
  • Supported by:
    Basic Public Welfare Research Project of Zhejiang Province（LGF22H260008, LGF20H260004）; Research Program of Zhejiang Provincial Institute of Dermatology（2021YJKT03, 2020YJKT07, 2018YJKT01）

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摘要： 【摘要】 目的 分析浙江省生殖器疱疹的流行特征和趋势，为制定防控策略提供依据。方法 从中国疾病预防控制信息系统传染病监测系统导出浙江省2011—2020年网络直报的生殖器疱疹病例数据，对病例资料进行描述性流行病学分析。结果 2011—2020年，浙江省生殖器疱疹报告发病率为4.92/10万 ~ 6.19/10万，无明显上升或下降趋势（χ2趋势 = 0.03，P = 0.959）；女性报告发病率呈上升趋势（χ2趋势 = 5.13，P = 0.034），由4.50/10万上升至6.02/10万，年均上升3.27%；高发年龄段为20 ~ 39岁性活跃人群，但15 ~ 19岁及50岁以上各年龄组报告发病率均呈上升趋势，年均增幅分别为8.10%（15 ~ 19岁）、9.24%（50 ~ 54岁）、7.81%（55 ~ 59岁）、4.27%（≥ 60岁）。病例职业构成以农民为主（28.38%，8 779/30 931），医务人员、离退人员、学生、家务及待业、干部职员职业构成比年均增幅居前，分别为13.71%、13.14%、10.74%、9.36%、7.00%。报告发病率较高的是宁波、温州、台州等东部沿海地区及浙江中部工业经济较发达的金华市，年报告发病率均在5/10万以上；杭州市年报告发病率明显上升，年均增幅5.39%。结论 2011—2020年浙江省生殖器疱疹疫情无明显下降趋势，今后需关注女性、青少年和老年人群的防治工作，加强单纯疱疹病毒感染状况监测及感染途径、接触史调查。

关键词: 生殖器疱疹, 发病率, 流行病学研究, 人口统计学, 浙江

Abstract: 【Abstract】 Objective To investigate epidemiological features and trends of genital herpes in Zhejiang province, and to provide scientific evidence for developing control strategies. Methods Data on reported cases of genital herpes in Zhejiang province between 2011 and 2020 were collected from national notifiable infectious disease surveillance system in China Disease Control and Prevention Information System, and a descriptive epidemiological study was conducted. Results The reported incidence rate of genital herpes in Zhejiang province between 2011 and 2020 ranged from 4.92 per 100 000 to 6.19 per 100 000, without a significant upward or downward trend （trend χ2 = 0.03, P = 0.959）; the reported incidence rate in females showed an increasing trend (from 4.50 per 100 000 to 6.02 per 100 000, trend χ2 = 5.13, P = 0.034）, with an average annual increase rate of 3.27%; among all the age groups, the sexually active population aged 20 - 39 years showed a high reported incidence rate of genital herpes, but the incidence rate increased significantly in the groups aged 15 - 19 years and over 50 years, with the average annual increase rates being 8.10%, 9.24%,7.81% and 4.27% in the groups aged 15 - 19 years, 50 - 54 years, 55 - 59 years and over 60 years respectively. The largest proportion of cases was found in farmers （28.38%, 8 779/30 931）, and high average annual increase rates in proportions were observed in healthcare workers, retirees, students, unemployed population and cadres （13.71%, 13.14%, 10.74%, 9.36% and 7.00%, respectively）. The reported incidence rates were high (over 5 per 100 000) in Eastern coastal areas such as Ningbo, Wenzhou, Taizhou, as well as Jinhua city with relatively developed industrial economies in central Zhejiang; the reported incidence rate markedly increased in Hangzhou city, with an average annual increase rate of 5.39%. Conclusions There was no obvious downward trend in the prevalence of genital herpes in Zhejiang province from 2011 to 2020. Attention should be paid to the prevention and treatment of genital herpes in females, adolescents and the elderly, and the monitoring of herpes simplex virus infections and investigation of infection routes and exposure history should be strengthened.

Key words: Herpes genitalis, Incidence, Epidemiologic studies, Demography, Zhejiang