中华皮肤科杂志 ›› 2020, Vol. 53 ›› Issue (10): 849-853.doi: 10.35541/cjd.20190432
刘海波1 曹华2 桑红1
收稿日期:
2019-03-26
修回日期:
2019-10-14
发布日期:
2020-09-30
通讯作者:
桑红
E-mail:shzwqzsl@163.com
基金资助:
Liu Haibo1, Cao Hua2, Sang Hong1
Received:
2019-03-26
Revised:
2019-10-14
Published:
2020-09-30
Contact:
Sang Hong
E-mail:shzwqzsl@163.com
Supported by:
摘要: 【摘要】 近年来,达标治疗策略在系统性红斑狼疮(SLE)治疗中取得了巨大进展。达标治疗理念认为,SLE患者治疗的主要目标是获得并保持临床缓解,如不能达到临床缓解,则以达到低疾病活动度为次要目标。达到治疗目标并维持一定时间后,则可尝试糖皮质激素逐渐减量,如有可能可以完全停用。在持续获得临床缓解的患者中,可继续尝试逐渐减停免疫抑制剂和抗疟药物。在保持低疾病活动度的患者中,则可尝试免疫抑制剂逐渐减量。达标治疗理念为SLE零激素与零用药指明了方向并提供了可能性。本文总结了SLE达标治疗的最新理念,探讨了该理念对SLE治疗中糖皮质激素、免疫抑制剂以及抗疟药减停的影响及指导意义。
刘海波 曹华 桑红. 系统性红斑狼疮零激素与零用药的可能性[J]. 中华皮肤科杂志, 2020,53(10):849-853. doi:10.35541/cjd.20190432
Liu Haibo, Cao Hua, Sang Hong. Possible discontinuation of glucocorticoids and complete withdrawal of therapy in patients with systemic lupus erythematosus[J]. Chinese Journal of Dermatology, 2020, 53(10): 849-853.doi:10.35541/cjd.20190432
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