Abstract: The frinction of humoral and.cellular immunity of 82 cases of cutaneous chromomycosis were determined and compared with normal controls.No abnormal changes were observed,In this report the probleuis about-immune spectrum and immunologie manifestatioas of patients with cutaneous chromomycosis were discussed.By the above results it showed that,,there,was.no significant immune spectrum in different clinical features.It was suggested,that the infection of the disease may be correlated to the specific immune response aad local immuoity.