Abstract: Teroatp patianta with chsoaic relspsiag pyoderna were treated,with corynebacteriuni anaerobic vaccine (CAY)with favourable results. These patients were given CAV 1-2 ml by intramuscular injections, once a-week(without other systemic therapp), 10 injections as a course.Of the 20 cases, 10 were cured,6 markedly-improved, 3 improved and 1 unchanged, Of the 14 cases followed up for more than 6 months, 10 were cured and 4 markedly improved. Half of the patients showed side-effects, such as mild paia, red and swelliag at the injection site,numbaess of the lower, fever etc. They.almost all disappeared 1-2 days.