Abstract: CHEN Ai-ming, GAO Ya-li, LI Na, YU Shan-shan, ZHANG Wei, LU Yan-hong. Department of Dermatology, First Affiliated Hospital, Suzhou University, Suzhou 215006, China Corresponding author: CHEN Ai-ming, Email: amchen0829@163.com 【Abstract】 A case of porokeratoma is reported. A 35-year-old man presented with asymptomatic verrucous nodules on both buttocks for more than 1 year. Skin examination at the first visit revealed two pea-sized verrucous nodules on bilateral buttocks. The lesions recurred at the primary site 3 months after surgical resection. At the second visit, there were 4 verrucous nodules, including 1 on the left buttock and 3 on the right buttock. Histopathological examination showed a well-defined lesion characterized by acanthosis and compact, thick orthokeratosis with seveal broad cornoid lamellae. A diagnosis of porokeratoma was made. The lesion was resected again followed by oral acitretin treatment. No recurrence was observed during 15 months of follow up.

Key words: Porokeratom