Abstract: ByⅡF,SDS-PAGE and Western blot technique,it was confirmed that there were germ tube-specific antigens on the surfaces of germ tubes of C.albicans which were isolated from clinical specimens.The mycelialphase extract of C.albicans contained a more varied array of proteins than those of the yeast-phase extract.We found a protein component (molecular weight,39 000)in cell wall extracts of mycelial-phase,which may be a germ tube-specific antigen of C.albicans.It is our opinion that there may be germ tube antigens in a cryptic state not only in the cell walls of yeast-phase of C.albicans but in other candida species.

Key words: C.albicans, Antigen,germ tubespecific