Abstract: This paper first reports on systemic lupus erythematosus with galactorrhea.From May 1994 to April 1995,we checked 48 female in-patients,in whom we found 9 cases,aged from 20 to 45 years,with various degrees of galactorrhea.The serum prolactin levels of 9 cases with galactorrhea were 45.86±28.84ng/ml and those of the rest 39 cases without galactorrhea were 21.43±14.92ng/ml,P<0.01.After following-up of the patients,we found that most patients treated with corticosteroid and im-munosuppressive agents galactorrhea modified and subsided,and their serum prolactin lowered as well. However,there was no apparent distinction in the involvement of main internal organs between the group with galactorrhea and the group without it.It indicated that galactorrhea and serum prolactin were parallel to the activity of the disease,but the appearance of galactorrhea did not reflect the severity of the disease.It may show that galactorrhea is one of the manifestations of the endocrine disorders in systemic lupus erythematosus.

Key words: Lupus erythematosus,systemic, Galactorrhea, Prolactin