过敏性接触性皮炎反应中浸润T细胞类型研究

Chinese Journal of Dermatology ›› 1997, Vol. 30 ›› Issue (4): 251-252.

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Study of the Type of Infiltrating T Cells in Allergic Contact Dermatitis

Bai Yalai¹, Zhang Chunlei¹, Zeng Lingfang²

Department of Dermatology, The 3rd Hospital of Beijing Medical University, Beijing 100083

Received:1996-09-03 Revised:1996-12-30 Online:1997-08-15 Published:1997-08-15

Abstract

Abstract: In order to investigate the type of infiltrating T cells in allergic contact dermatitis (ACD) reaction, by the methods of RT-PCR and immunohistochemistry, we tried to detect IL-2mRNA, IL-2, IFN-γ, IL-4 in the lesions of patients with ACD. The results showed that Th1 cytokines were expressed aberrantly in ACD patients and Th1-like clone which secrets IL-2, IFN-γ appeared to be predominant in ACD reaction.

Key words: Dermatitis, contact, Interleukin-2, Interferon γ

Bai Yalai, Zhang Chunlei, Zeng Lingfang. Study of the Type of Infiltrating T Cells in Allergic Contact Dermatitis[J].Chinese Journal of Dermatology, 1997, 30(4): 251-252.

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Study of the Type of Infiltrating T Cells in Allergic Contact Dermatitis

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