光线性角化病皮损的细胞DNA含量流式细胞分析

Abstract

Abstract: Actinic keratosis (AK) is a precancerous state of the skin, which shows epidermal dysplasia of different degrees. The cellular DNA content and proliferative activity of the skin lesions in 27 cases of AK were analyzed with flow cytometry. The results showed that the PI (proliferating index) in AK was higher than that in normal skin (P<0.05). Among 27 eases of AK, the cellular DI (DNA index) of 8 cases of severely dysplastie AK was higher than the rest 19 cases (P<0.05). The results suggest that the cells in the skin lesions of AK proliferate actively, and the higher the degree of dysplasia showed in AK the more the significance of aberration of DNA content.

Key words: Keratosis actinic, DNA

Li Yuping, Liao Haiying, Sun Xiurong. Analysis of Cellular DNA Content of Skin Lesions in Actinic Keratosis with Flow Cytometry[J].Chinese Journal of Dermatology, 1997, 30(4): 246-247.

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Analysis of Cellular DNA Content of Skin Lesions in Actinic Keratosis with Flow Cytometry

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