Abstract:

A 51-year old male patient, who was suffered from extensive erythema, keratoderma, poikiloderma and acral blister formation for seven years, together with skin atrophy, photosensitivity, syndactyly, mucosal involvement, nail dystrophy, entropion of the eye lids, palmoplantar keratoderma, pseudoainhum and dental caries. Histopathology examination showed mild hyperkeratosis and atrophy of the epidermis, liquefaction degeneration of basal cell and colloid bodies. There was a subepidermal cleft, many melanophages and free pigments were observed in upper dermis. Suspected diagnosis: Weary-kindler syndrome.

Key words: Weary-kindler syndrome, acrokeratotic poikiloderma