Abstract: Zhang Zhenzhen, Meng Yuan, Li Ping, Li Jianhong, Tang Pengyue, Liu Jianzhong Zhuhai Campus of Zunyi Medical University, Zhuhai 519041, China （Zhang ZZ ［current affiliation: Enze Hospital of Taizhou Enze Medical Center, Taizhou 318000, Zhejiang, China］）; Department of Dermatology, Shenzhen Children′s Hospital, Shenzhen 518038, China （Meng Y, Li P, Li JH, Tang PY, Liu JZ） Corresponding author: Li Ping, Email: liping20081110@126.com 【Abstract】 Objective To investigate the prevalence of and influencing factors for atopic dermatitis（AD）in children aged 1 - 7 years in Shenzhen city, and to analyze difference in diagnostic results between two diagnostic criteria. Methods From December 1st 2013 to March 1st 2014, a questionnaire survey and physical examination were conducted to investigate the prevalence of AD in children aged 1 - 7 years in Shenzhen city. Results A total of 1 504 children were enrolled into this study, including 716 males and 788 females. Based on the clinical diagnosis by experienced dermatologists, the prevalence of AD was 11.84% （178/1 504） in total, 11.73% （84/716） and 11.93% （94/788） in males and females, respectively, and there was no significant difference in the prevalence of AD between males and females （χ2 = 0.01, P > 0.05）. Based on the Williams′ diagnostic criteria, the prevalence of AD was 3.92% （59/1 504） in total, and 4.05% （29/716） and 3.81% （30/788） in males and females, respectively. Premature birth was a risk factor for the occurrence of AD（χ2 = 5.43, P < 0.05）. Conclusions The prevalence of AD is evidently increased among children aged 1 - 7 years in Shenzhen city, and premature birth is a risk factor for AD. Missed diagnosis will be reduced based on clinical diagnosis by experienced dermatologists.