Abstract:

Wei Xuhua, Zhang Jiang′an, Yu Jianbin, Li Xiaohong, Zhao Bingjie, Lyu Yan, Shi Weihua Department of Dermatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China Corresponding author: Zhang Jiang′an, Email: zja816@163.com 【Abstract】 A 26-year-old male patient presented with facial depigmented patches for 10 years, some of which turned to blue-grey 7 years prior to the presentation. Before the white patches turned blue-gray, the patient developed contact dermatitis due to topical application of self-made drugs. Skin examination showed blue-gray hyperpigmentation on the left upper lip and in the temporal region, with white hairs in the hyperpigmented lesions on the left upper lip. Dermoscopy revealed irregularly shaped, light to dark blue-gray patches on the left upper lip, which were intermingled with white patches in some regions, and white hair stubs were observed in the white patches. Histopathological examination of temporal lesions showed decreased melanocytes in some regions in the epidermis, pigmentation in both basal and suprabasal layers, perivascular infiltration of a small number of chronic inflammatory cells and melanophages in the superficial dermis, and melanophage infiltration around sweat ducts. Finally, the patient was diagnosed with blue vitiligo. He refused to receive any treatments, and follow-up was under way.