Chinese Journal of Dermatology

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A case of primary cutaneous mucormycosis caused by Mucor racemosus Fres. var. chibinensis Schipper

WANG Jun-jie1, WU Yan-hong1, LIANG Jie1, FAN Jian-yong1, HE Jing-zu1, YANG Hui-lan1, CHENG Li-yang2, QI Xiang-dong3, LI Qin3, TIAN Ye4, CHEN Xiao-dong4   

  1. Department of Dermatology, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou 510010, China
  • Received:2006-11-13 Online:2007-08-15 Published:2007-08-15

Abstract: Objective To report a case of primary cutaneous mucormycosis caused by Mucor racemosus Fres.vat.chibinensis Schipper.Methods The patient was a 22-year old woman,presenting with a nodule on the left hip,which had gradully enlarged for 6 years and exhibited verrucous proliferation for 1 year.Other possible diseases were ruled out by overall clinical examination.The isolate was identified via direct microscopic examination,culture,temperature test,pathological examinaiton and PAS staining.Results Pathological examination disclosed an infectious granuloma with the proliferation of eosinophils.Long,thick and nonseptate hypha were found by H&E staining,PAS staining,silver staining,and microscopic examination.The culture (7 days,at 25℃) from the lesion yielded exuberant yellow colonies.The isolate was identified as Mucor racemosus Fres.vat.chibinensis Schipper.The fungal granuloma was resected and the defect repaired with medium thickness skin flaps;the patient was also given systemic antifungal agents.One month later,the patient achieved clinical and mycological recovery.Conclusions This is a case of primary cutaneous mucormycosis due to Mucor racemosus Fres.var.chibinensis Schipper.Surgical resection and skin grafting combined with systemic antifungal agents are safe and effective for the management of this condition.

Key words: Mucormycosis, Mucor