Abstract:

Wang Jian, Gong Xiangdong, Wu Minzhi, Zhao Liang Division of Sexually Transmitted Disease Epidemiology, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China （Wang J, Gong XD）; Department of Dermatologic Surgery, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China （Zhao L）; Department of Dermatology, Fifth People′s Hospital of Suzhou, Suzhou 215007, China （Wu MZ） Corresponding author: Gong Xiangdong, Email: gxdchina@163.com 【Abstract】 Mother-to-child transmission （MTCT） is a major route of transmission of syphilis, and may occur at any time during pregnancy. MTCT of syphilis can lead to many adverse pregnancy outcomes, seriously affects maternal and infant health, and has been a severe public health and social problem. The risk of MTCT of syphilis is associated with stage of syphilis in pregnancy, stage of pregnancy, receiving or not receiving treatment, and is especially high in patients with early syphilis. With the growth of incidence of syphilis, the prevention for MTCT of syphilis has been becoming more and more important. Screening for and early treatment of syphilis in pregnancy can effectively block MTCT of syphilis. To learn the epidemiology, route, risk, and associated factors of MTCT of syphilis will undoubtedly facilitate the development of strategies for syphilis prevention and control.