Abstract: LI Mei-jiao*, WANG Peng, CAI Min, LIU Qiao, WU Wei-wei, FU Lei, MENG Bing-xin, CHEN Mei-xiong, WU Shao-qiang, FU Guang-xiong, LIN Shao-fei, CHEN Jin-yan. *Department of Dermatology, Hainan Provincial Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Chinese Medicine, Haikou 570203, China Corresponding author: LI Mei-jiao, Email: meijiaopfk@126.com 【Abstract】 Objective To estimate the prevalence of psoriasis in resident population in Hainan province through a large-scale, multi-center epidemiological survey. Methods Ten small towns or communities were selected from each of 18 cities or counties in Hainan province as survey sites. Multi-stage sampling strategies （including stratified sampling, simple random sampling and cluster sampling） were used in this study. After respondents signed an informed consent form, investigators completed a registration form containing information regarding clinical features of psoriasis, environmental factors, character trait, aggravating factors, trauma history, infection history, etc. Statistical analysis was carried out by the EpiData 3.1 and SPSS 17.0 software. Results This study recruited 35 314 subjects, and 30 935 responded with a return rate of 87.60%. The ratio of man to women was 1.2 ∶ 1, with an average age of（33.86 ± 17.78） years. Forty-six cases of psoriasis were confirmed in these respondents. The overall and standardized prevalence rate of psoriasis was 1.49‰ and 1.42‰ respectively. A significant increase was observed in the standardized prevalence rate of psoriasis in males compared with females（1.85‰ vs. 0.84‰, χ2 = 6.86，P < 0.01）. The average age of onset was （33.49 ± 14.61） years, and the most common clinical type was psoriasis vulgaris （82.60%, 38/46）. Anxiety was the risk factor of psoriasis. The impact of psoriasis on the quality of life included barriers to social （89.13％） and physical activity （73.91％） as well as psychological disorders （86.97%）. Conclusions The prevalence rate of psoriasis in resident population in Hainan province is lower than the national average level in China. It seems that multiple factors are implicated in the initiation and progression of psoriasis. 【Key words】 Psoriasis; Epidemiology; Hainan

Key words: Prevalence