Abstract:

Objective To make a survey on common cosmetic allergens, and to provide epidemiological data and clinical evidence for cosmetic allergy. Methods Patch test was performed by using 49 cosmetic allergens from a European cosmetic series and 5 Chinese standard screening allergens on 89 patients with suspected cosmetic allergic contact dermatitis. Test results were determined according to the International Contact Dermatitis Research Group （ICDRG） recommendation. Results Of the 89 patients, 61 （68.5%） showed positive reactions to one or more cosmetic allergens. The most common allergens were fragrances （33.7%）, followed by preservatives （30.3%）, para-phenylenediamine （25.8%） and amerchol L 101（10.1%）. Conclusion Fragrances, preservatives, para-phenylenediamine and amerchol L 101 are dominant causative allergens in patients with cosmetic allergic contact dermatitis.

Key words: Patch test