Chinese Journal of Dermatology ›› 2011, Vol. 44 ›› Issue (7): 513-514.

• Research reports • Previous Articles     Next Articles

Measurement of transforming growth factor (TGF)-β1 in sera of patients with psoriatic arthritis

  

  • Received:2010-09-15 Revised:2010-11-16 Online:2011-07-15 Published:2011-07-12

Abstract:

Objective To measure the expression of TGF-β1 in the sera of patients with psoriatic arthritis and its significance. Methods The serum level of TGF-β1 was measured in 38 patients with psoriatic arthritis and 80 patients with psoriasis vulgaris. Results A significant difference was observed between the patients with psoriatic arthritis and those with psoriasis vulgaris (375.92 ± 95.883 pg/ml vs. 510.78 ± 167.967 pg/ml, t = 4.60, P < 0.01). Conclusion Continuous monitoring of serum levels of TGF-β1 may help clinicians to take precautions against osteoporosis in patients with psoriatic arthritis.

Key words: osteoporosis