Chinese Journal of Dermatology ›› 2011, Vol. 44 ›› Issue (7): 465-467.

• Original articles • Previous Articles     Next Articles

Atrophic dermatofibrosarcoma protuberans: 2 case report

2, Yi-Qun JIANG2,   

  • Received:2010-09-07 Revised:2010-09-23 Online:2011-07-15 Published:2011-07-12

Abstract:

Two cases of atrophic dermatofibrosarcoma protuberans (DFSP) are reported. The patients were a 16-year-old and a 24-year-old boy with a clinical course of 6 and 5 years respectively. The lesions began as well-marginated atrophic erythema, and subcutaneous nodules appeared gradually on the erythema. Histopathology showed atrophic or normal epidermis, wavy arrangement of tumor (spindle) cells in the superficial dermis which was aligned parallel to the epidermis, storiform arrangement of tumor cells in the lower dermis, and typical lacelike pattern of infiltration of subcutaneous fat tissue with tumor cells. Immunohistochemistry showed that the tumor cells stained positive for vimentin and CD34, but negative for S100 or CD 68.

Key words: CD34