Abstract:

one case of seborrheic keratosis accompanied with Meyerson phenomenon was reported. A 65-year-old male presented with brown papules on his left upper back and left leg for more than 20 years and erythema, papules and exudation around the original brown papules with itchy for more than 2 months. Physical examination showed that there were one 0.5cm in diameter sized brown papules on his left leg and left upper back respectively. Each papule was surrounded by a 1-1.5cm in diameter circumscribed erythema accompanied with papules, scales and mild exudation. The brown papules in the center had a clear border and had no ulceration or bleeding. The histopathological changes of both lesions from the back and left leg were similar: the brown papules from the center of the lesions showed acanthosis with edema, pseudokeratotic cysts in and a flattened base of the epidermis, perivascular chronic inflammatory infiltration in the superficial dermis. The samples from the surrounding eczematous changes of the brown papules showed hyperkeratosis, parakeratosis, acanthosis, spongiosis of the epidermis, an infiltration composed of lymphocytes, histiocytes and a few eosinophils in the dermis and perivascularly. The final diagnosis was seborrheic keratosis accompanied with Meyerson phenomenon.

Key words: Meyerson phenomenon