Abstract:

Objective To assess the histopathological characteristics of tumors arising in nevus sebaceous. Methods The clinical and pathological data on 16 patients with tumors arising in nevus sebaceous were collected and retrospectively reviewed. Histopathological characteristics were analyzed. Results Of the 16 patients, 12 aged ≥18 years, 4 aged 11 to 17 years; 7 had syringocystadenoma papilliferum（SCAP）, 4 tubular apocrine adenoma（TAA）, 3 trichilemmoma, 2 basal cell carcinoma（BCC）, 1 porokeratotic eccrine ostial and dermal duct nevus, and 1 nevus flammeus. Six patients suffered from more than one kind of tumor; of these tumors, concurrent syringocystadenoma papilliferum and apocrine adenoma predominated and were observed in 4 of these patients. Conclusion Any tumor arising from nevus sebaceous should be closely followed up.