皮肤免疫系统与光致癌

Abstract

Abstract:

Ultraviolet radiation can induce skin photocarcinogenesis. Skin immune system (SIS) is consist of immune cells and humoral components. Cell components of SIS include langerhan’s cell, mast cell, lymphocyte, keratinocyte, and others. Humoral components of SIS include cytokine, complement, prostaglandin and others. SIS plays an essential role of maintaining skin homeostasis. Ultraviolet radiation can damage the function of SIS for antigen presenting and immunosurveillance, and induce immunosuppression. These all can initiate and promote the Ultraviolet-related skin carcinogenesis. Research on SIS is important to elucidate the mechanism of photocarcinogenesis. Furthermore, we can apply immunological methods to prevent and treat the ultraviolet-related skin carcinogenesis.

Key words: photocarcinogenesis

Qi Bei HUANG Dan. Skin immune system and photocarcinogenensis[J].Chinese Journal of Dermatology, 2011, 44(1): 64-66.

References

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Skin immune system and photocarcinogenensis

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