[1]Andrew J.S， James E. G.D，Jaleel A. M. .Without nerves, immunology remains incomplete – in vivo veritas. [J].Immunology,2005,116:145-163 [2]Zdenek H， Milos G, Klaus I.B. Friedrich Sigmund Merkel and His“Merkel Cell”, Morphology,Development, and Physiology: Review and New Results[J].Anat Rec Part A,2003,271A:225- [3]Misery L.Neuro-immuno-cutaneous system (NICS)[J].Pathol Biol (Paris,1996,44(10):867-874 [4] O'Sullivan RL, Lipper G, Lerner EA. The neuro-immuno-cutaneous-endocrine network: relationship of mind and skin. Arch Dermatol. 1998 ;134(11):1431-1435[5]Roosterman D, Goerge T, Schneider SW,et al.Neuronal Control of Skin Function:The Skin as a Neuroimmunoendocrine Organ[J].Physiol Rev,2006,86:1309-1379 [6] Chan J, Smoller BR, Raychauduri SP,et al. Intraepidermal nerve fiber expression of calcitonin gene-related peptide,vasoactive intestinal peptide and substance P in psoriasis. Arch Dermatol Res；1997;289(11):611-616[7] Jiang WY，Raychaudhuri SP,Farber EM.Double-labeled immunofluorescence study of cutaneous nerves in psoriasis.Int J Dermatol;1998;37(8):572-574[8]姚聪君　王俊民　谭升顺等.银屑病患者皮损内及血中神经肽(SP、SS) 的研究[J].中国皮肤性病学杂志,1998,12(1):5-6 [9]Kramp J,Brown J,Cook P,et al.Neuropeptide induction of human microvascular endothelial cell interleulcin-8[J].J invest Dermatol,1995,104(4):586- [10]Ogata A, Nishimoto N, Yoshizaki K.Advances in interleulcin-6 therapy[J].Rinsho Byori,1999,47(4):321-326 [11]Pfundt R,Wingeus M,Bergers M,et al.TNF-alpha and serum induce SKALP/elafin gene expression in human keratinocytes by a p38 MAP kinase-dependent pathway[J].Arch Dermatol Res,2000,292(4):180-187 [12]Richard L.Eckert, Ann-Marie Broome,Monica Ruse,et al[J].S100 Proteins in the Epidermis. J Invest Dermatol,2004,123:23- [13]Ann-Marie Broome, David Ryan, Richard L.Eckert.S100 Protein Subcellular Localization During Epidermal Differentiation and Psoriasis[J].The Journal of Histochemistry & Cytochemistry,2003,51(5):675- [14]D Reinhold, A Biton, S Pieper,et al.Dipeptidyl peptidase IV (DP IV, CD26) and aminopeptidase N (APN, CD13) as regulators of T cell function and targets of immunotherapy in CNS inflammation[J].Int Immunopharmacol,2006,6(13-14):1935-1942 [15]Thielitz A, Ansorge S, Bank U, et al.The ectopeptidases dipeptidyl peptidase IV (DP IV) and aminopeptidase N (APN) and their related enzymes as possible targets in the treatment of skin diseases[J].Front Biosci,2008,13:2364-2375 [16]Gabrilovac J, Cupic B, Breljak D, et al.Expression of CD13/aminopeptidase N and CD10/neutral endopeptidase on cultured human keratinocytes[J].Immunol Lett,2004,91(1):39-47 [17]Zdenek H， Milos G, Klaus I.B. Friedrich Sigmund Merkel and His“Merkel Cell”, Morphology,Development, and Physiology: Review and New Results[J].Anat Rec Part A,2003,271A:225- [18]Tamiko T，Tokio N.Immunohistochemical reactions of receptore to VIP, substance P，and CGRP located on Merkel cells in the sinus hair follicle[J].Arch Histol Cytol,2005,68(5):383-391 [19] Tamiko T，Makoto E，Naoki F，et al. Receptors and transporter for serotonin in Merkel cell－nerve endings in the rat sinus hair follicle. An immunohistochemical study.Arch Histol Cytol. 2005；68（1）：19-2[20] Andrés B.F,Rosalía G,Montserrat B, et al. Merkel cells, a new localization of prepro-orexin and orexin receptors. J. Anat.2004;204:117–122[21]Steinhoff M,Stander S,Seeliger S,et al.Modern aspects of cutaneous neurogenic inflammation[J].Arch Dermatol,2003,139:1479-1488 [22]Barrett AW, Cort EM, Patel P, et al.An immunohistological study of cytokeratin 20 in human and mammalian oral ep ithelium [ J ][J].Arch Oral Biol,2000,45(10):879- [23] De BerkerD, Wojnarowska F, Sviland L, et al. Keratin exp ression in the normal nail unit:markers of regional differentiation[ J ]. Cell Tissue Res, 2000 Jan, 142 (1) : 89 - 90