Abstract:

This paper reports one case of primary cutaneous CD30 + large cell lymphoma. The right forearm skin appears inflammation, infiltration and ulcer incrustation for one month; the left head and face appear inflammation and infiltration for ten days. Pathological examination on right forearm cutaneous lesions: at the deep dermal layer and between subcutaneous adipose tissues the tumor cells appear infiltration and intensive distribution; the tumor cells are rich in cytoplasm and are eosinophilic; some show vacuoles shape, big nucleus, obvious atypia and obvious nucleoli, the chromatin showing coarse granular shape, and there is pathological karyokinesis; a small amount of sophisticated lymphocytic appear infiltration. Immunohistochemistrical examination shows tumor cells CD45R0 (+), CD30 (+), CD68 (-), CD20 (-), EMA (-) and ALK (-). Thus it is diagnosed as Primary Cutaneous Anaplastic Large Cell Lymphoma