Abstract: A 13-year-old girl presented with a 9-year history of hydroa vacciniforme(HV)-like eruption,including erythema,papules and vesicles,mainly distributed at the face and extremities.A high fever(>39℃)developed at the progressive stage of this disease.Physical examination showed variously sized,round or oval,atrophic and variola-like scars along with scattered erythematous patches,papules, necrosis and crusts on the face and extremities.The face was edematous,and there were some edematous and erythematous plaques with a necrotic center on the legs and arms.Histological examination revealed a massive infiltration with atypical CD8⁺ lymphocytes around the vessels and appendages in dermis.A diagnosis of CD8⁺ cutaneous T-cell lymphoma(CTCL)was made.Glucocorticoid and immunosuppressants were effective in controlling the condition.Up to the time of the writing,there has not been any definite evidence of systemic involvement.

Key words: Lymphoma, T-cell, cutaneous, CD8-positive T-lymphocytes, Hydroa vacciniforme