Abstract: Objective To study the effect of long pulsewidth 800 Diode Laser in hair removal technique on the function of the axillary sweat gland.Methods Fourteen volunteers undergoing 5 hair removal treatments using long pulsewidth Diode Laser were studied under auto-control study.After the last treatment,the overall excretion of the axillary sweat glands of all volunteers were measured using gravimetric technique,skin biospies from6volunteers were studied histologically,and one under electronmicroscopy.Results After5hair removal treatments,the axillary hairs were removed almost completely,with excellent therapeutic effect.At the end of the study,the excretion rate of sweat on the treatment side was:7.1247.124±8.190mg/cm² ·h,while the control side 7.880±10.075mg/cm²·h,there was no statistical difference(P>0.05).No significant histological and ultrastructural changes were observed in the skin biopsies.Conclusion The long pulsewidth Diode Laser is a safe hair removal technique with good result and without adverse effect on the function of axillary sweat gland excretion.

Key words: Hair removal, Epilating laser, Sweat gland