Abstract: Objectives To investigate the etiology of genital ulcer diseases in sexually transmitted disease clinics.Methods The specimens from genital ulcers of 165 patients attending sexually transmitted disease clinics were detected for Haemophilus ducreyi,Treponema pallidum,and herpes simplex virus by a multiplex PCR,dark field microscopy and syphilitic serology.Results There were 51 (30.9%) cases of syphilis and 52 (31.5%) cases of genital herpes among 165 patients,respectively.No chancroid case was found.No pathogen was detected in remaining 62 (37.6%) patients.Conclusion Syphilis and genital herpes predominate in genital ulcer diseases in our sexually transmitted disease clinic patients.

Key words: Genitalia, Ulcer, Syphilis, Genital herpes, Polymerase chain reaction