不同时期分离的淋病奈瑟菌药物敏感性测定

Abstract

Abstract: Objective To study the changes of susceptibilities of Neisseria gonorrhoeae to antibiotics in Chengdu area.Methods The MIC values of 12 antibiotics to 100 strains in 1991 and 100 strains in 1996 were determined,and the MIC values to PPNG and non-PPNG strains were also compared.Results and Conclusion The MIC values of 6 antibiotics (including penicillin G,tetracycline,etc.) to the isolates in different periods changed significantly (P<0.05 or P<0.01),and among them the values of MIC₅₀ of penicillin G and norfloxacin in 1996 had a 63 fold increase over those in 1991.Moreover,there was a difference in MIC values between PPNG and non-PPNG strains.

Key words: Neisseria gonorrhoeae, Microbial sensitivity tests

Xiang Hui, Yong Gang, Ye Meijun. Study on Susceptibility of Neisseria Gonorrhoeae Isolated from Chengdu in Different Periods[J].Chinese Journal of Dermatology, 1998, 31(3): 166-167.

[1]	. [J]. Chinese Journal of Dermatology, 2005, 38(12): 766 .
[2]	SHI Jian-qiang, CHEN Rong-yi, FAN Yi-ming, WU Zhi-hua. Cell Apoptosis and mRNA Expression of c-fos and BNIPl in Cutaneous Squamous and Basal Cell Carcinomas[J]. Chinese Journal of Dermatology, 2005, 38(10): 631 -633 .
[3]	. [J]. Chinese Journal of Dermatology, 2005, 38(10): 647 .
[4]	SUN Lin-chao, ZHAO Xiao-dong, LIU Yu-feng, FAN Ping-shen, LI Cheng-xin, LU Tao, LI Wei, GAO Tian-wen. Effects of Anti-Keratin Autoantibody on Apoptosis of Cultured Human Keratinocytes[J]. Chinese Journal of Dermatology, 2005, 38(9): 572 -574 .
[5]	. [J]. Chinese Journal of Dermatology, 2005, 38(9): 588 .
[6]	顾敏, 狄梅. [J]. Chinese Journal of Dermatology, 2005, 38(5): 321 .
[7]	苏勤, 陈永平, 凌淑清, 陆洪光. [J]. Chinese Journal of Dermatology, 2005, 38(3): 159 .
[8]	WANG Li-ying, CHEN Kun, CHANG Bao-zhu, GU Heng, ZHENG Jia-run. Determination of Minimal Erythema Dose of Normal Skin to Ultraviolet Rays[J]. Chinese Journal of Dermatology, 2005, 38(2): 80 -82 .
[9]	LIU Quan-zhong, YAO Wei-feng, QI Man-li, LI Yan, WANG Hui-ping, TIAN Jin-qun. Cloning,expression and identification of chlamydial GPIC capsid Vp1 protein[J]. Chinese Journal of Dermatology, 2006, 39(12): 714 -716 .
[10]	许冰, 王勇刚, 吴灵娇. [J]. Chinese Journal of Dermatology, 2006, 39(4): 219 -220 .

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Study on Susceptibility of Neisseria Gonorrhoeae Isolated from Chengdu in Different Periods

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