Chinese Journal of Dermatology ›› 1996, Vol. 29 ›› Issue (2): 77-79.
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Yang Xueqin1, Zhang Haitao2, Lida Naoko3
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Abstract: The expression of CD44 in psoriatic epidermis was studied with immunohistochemical staining. Overexpression of CD44-was observed in involved proliferative epidermis as compared with uninvolved and cured epidermis in psoriatic patient. Several CD44-isoforms based on analysis by reverse-transcriptase polymerase chain reaction (RT-PCR) were mainly CD44 S and CD44 E. These results suggest that CD44 may be an important substance in the proliferation of keratinocytes, such as psoriasis.
Key words: Psoriasis CD44
Yang Xueqin, Zhang Haitao, Lida Naoko. Expression of CD44 Molecules in Psoriatic Epidermis[J].Chinese Journal of Dermatology, 1996, 29(2): 77-79.
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