Chinese Journal of Dermatology ›› 1995, Vol. 28 ›› Issue (6): 370-371.

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Pyoderma Gangrenosum Caused by Fusarium Solani

Liao Wanqing, Li Zhigang, Xu Hong   

  1. Department of Dermatology, Changzheng Hospital. Second Military Medical University, Shanghai 200003
  • Received:1994-07-25 Revised:1994-10-24 Online:1995-12-15 Published:1995-12-15

Abstract: A 58-year-old male patient was admitted in January 1992 for a trauma of left eyelids caused by iron slag over 17 days.On examination he exhibited erythema, swelling, festering, necrosis, crust and deep ulcer involving subcutaneous and muscular layers of his lids, left temple and nose, A large amount of fungal hyphae were found on direct microscopy and histopathological examination.Same strain, CZ9213, grew on mycological culture medium for & times.The strain was identified as Fusarium solani (Mart) Sacc.by morphological characteristics, physiological features, and animal experimentation.The patient was cured by fluconazole in combination with 5-flucytosine.

Key words: Pyoderma gangrenosum, Fusarium, Fluconazole, Flucytosine