Abstract: Anticardialipin antibody level was measured by ELISA in 27 patients with SLB, 20 psoriasis, 16 dermatomyositis, 10 progressive systemic sclerosis, 54 normal controls. Blood coagulation changes were also investigated in SLE patients. The results show that not only the level and positive rate of anticardiolipin antibody in SLE were significantly higher than those of other groups, but also the index of disease activity correlated positively with the level of anticar-diolipin antibody in SLE patients. Abnormal blood coagulation changes most often observed in these patients were the increase of FDP and Fbg, prolonged or shortened KPTT time, etc. However, no significant correlationship was observed between the blood coagulation paramcters and the level of anticardiolipin autibody. The factors concerned were discussed.

Key words: Lupus erythcmatosus, systemic, Anticardiolipin antibodies, Blood coagulation