Chinese Journal of Dermatology ›› 1989, Vol. 22 ›› Issue (6): 392-394.

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ACUTE SKIN IRRITATION TEST IN ANIMALS-A COMFARiSON BETWEEN THE HISTOLOGICAL EXAMINATION AND MACROSCOPICAL EVALUATION

FANG Jia-Lin, LIU Ji-He   

  1. Institute of Dermadology, Chinese Academy of Medacal Sciences, Nanjing
  • Received:1988-05-16 Revised:1988-09-14 Online:1989-12-15 Published:1989-12-15

Abstract: Using the animal patch test,the authors compared the histoiogical scoring with the visual assessment described by Draize,and found that there was a positive correlation between the two different methods,and considered-W at the histological scoring might be used,wand ehc present results also piovided a basis for ftrrmuIating the histological criteria in the assessment of intensity of irritation.