Abstract: Tlie values of PHA-lympliocyte transformation In 37 normal persons were above 5000 cpm; however, the values in 15 cases among 47 patients with systemic lupus erytliematosus(SLE)were below 5000 cpm. The difference of average. values of lympliocyte transformation between these two groups was quite significant, Four out of 37 normal persons lacked suppressor function of mononuclear cells, and so,did seven out of 47 patients. The difference between. the two proportions; 4/37(normal group)and 7/47(patient group), had no statistical significance. The compazisons of the active SLE patient group with the non-active group in PHA-lymphocyte transformation and suppressor function of mononucfear cells showed that there were no significant differences.