Abstract: Two patients, with mycosis fungoides have been reported. Frozen specific skin lesion sections were examined using indirect immuaoperoxidase tachnique with various monoclonal and polpclonal antibodies against T lymphocyte, T subsets, B lymphocyte, monocyte and Ia antigen. In the cases examined a predominance of cells with helper T cell markers and Ta positive was found. The discrepancy of some results were discussed.