Abstract: A simplified examination method of nitroblue tetrazolium(NBT) test was presented.The NBT test was studied in 100 patieats with 15 kinds of skin diseases.The results were as follows:the rate of NBT-positive cell increased is six kinds of bacte rial infections(such as impetigo etc)(p<0.051,and three kinds of fuagous diseases(such as tiaea pedis,tines manus,aad spototrichosis)(p<0.05);aormal in three kinds of viral diseases(such as herpes simplex etc)(p>0.05); decreased in 5 cases of psoriasis vulgari(p<0.05).