单细胞RNA测序技术及其在皮肤病学研究中的应用

doi:10.3760/cma.j.issn.0412-4030.2019.07.015

Abstract

Abstract: 【Abstract】 Single-cell RNA sequencing is a method for transcriptome profiling at the single-cell level, and is a hotspot technology in the field of biological research currently. Compared with the common high-throughput RNA sequencing, single-cell RNA sequencing can distinguish the biological differences between single cells, and identify rare cell populations and subpopulations. This review mainly describes the single-cell RNA sequencing method, summarizes current application of this technique in the field of dermatology, and discusses limitations and prospects of this technique.

Key words: Sequence analysis, RNA, Single?cell RNA sequencing, High?throughput RNA sequencing, Dermatology, Genetic heterogeneity

Zhu Ronghui, Li Wei. Single-cell RNA sequencing and its application in dermatology[J].Chinese Journal of Dermatology, 2019, 52(7): 506-509.

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Single-cell RNA sequencing and its application in dermatology

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