表皮生长因子受体抑制剂相关甲沟炎的研究进展

doi:10.35541/cjd.20210858

Abstract

Abstract: 【Abstract】 Epidermal growth factor receptor inhibitor （EGFRI）-related paronychia is a condition clearly related to EGFRI therapy, characterized by periungual erythema, edema, purulent exudates, periungual or subungual granulomatous lesions, and sometimes accompanied by thinning, fragility or even splitting and seperation of nail plates. Inhibition of epidermal function, inflammation and secondary infections, as well as angiogenesis are the core processes in the occurrence and development of EGFRI-related paronychia. This review summarizes epidemiology, pathogenesis, clinical manifestations, prevention and treatment of EGFRI-related paronychia.

Key words: Paronychia, Epidermal growth factor receptor inhibitors, Cutaneous adverse reactions

CLC Number:

Hu Zixin, Tan Kexin, Dong Huijing, Zhang Xu, Yu Yixuan, Lu Xingyu, Li Jia, Cui Huijuan. Epidermal growth factor receptor inhibitor-related paronychia[J]. Chinese Journal of Dermatology, 2025, 58(3): 276-281.doi:10.35541/cjd.20210858

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Epidermal growth factor receptor inhibitor-related paronychia

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