中华皮肤科杂志 ›› 2012, Vol. 45 ›› Issue (4): 293-295.

• 综述 • 上一篇    下一篇

恶性黑素瘤的治疗进展

梁鹏,陈学忠,宋建明,瞿平元   

  1. 甘肃省肿瘤医院
  • 收稿日期:2011-06-01 修回日期:2011-08-10 出版日期:2012-04-15 发布日期:2012-03-30
  • 通讯作者: 梁鹏 E-mail:liangpeng0801@sina.com

Advances in the treatment of malignant melanoma

  • Received:2011-06-01 Revised:2011-08-10 Online:2012-04-15 Published:2012-03-30
  • Contact: peng liang E-mail:liangpeng0801@sina.com

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摘要：

恶性黑色素瘤是高度恶性的皮肤肿瘤，外科手术是主要的治疗手端，早期发现早期手术大多可取得良好的疗效；氮烯咪胺仍是黑色素瘤化疗的金标准，有效率10%~25%，中位生存期仅8个月，联合化疗与生物化疗虽然提高了总反应率，但却未能改善总生存，一旦远处转移，难以控制，预后极差。氮烯咪胺、替莫唑胺等联合靶向治疗的疗效尚不肯定。

关键词: 治疗

Abstract:

Malignant melanoma is a highly malignant skin cancer, surgery is the primary treatment of hand, most of the early detection of early surgery can achieve good effect, dacarbazine is still the gold standard chemotherapy for melanoma, with efficiency of 10% to 25% The median survival of only 8 months, although the combined chemotherapy and bio-chemotherapy improved overall response rate, but failed to improve overall survival, once distant metastases is difficult to control, very poor prognosis. dacarbazine, such as temozolomide efficacy of combined targeted therapy is uncertain.

Key words: treatment

中图分类号: 

  • R730.26