中华皮肤科杂志 ›› 2008, Vol. 41 ›› Issue (5): 333-334.

• 短篇论著 • 上一篇    下一篇

129例颜面再发性皮炎患者斑贴试验临床分析

康定华 康莉 徐春兴 龚晓文 毕志刚   

  1. 江苏省常州市第一人民医院皮肤科 江苏省常州市第一人民医院皮肤科 南京医科大学第一附属医院皮肤科
  • 收稿日期:2007-08-06 修回日期:2007-10-22 发布日期:2008-05-15
  • 通讯作者: 康定华 E-mail:kangdinghua@163.com

Clinical analysis of patch test in 129 patients with facial recurrent dermatitis

  

  • Received:2007-08-06 Revised:2007-10-22 Published:2008-05-15

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摘要： 目的：通过斑贴试验研究颜面再发性皮炎的病因。方法：对临床诊断为颜面再发性皮炎的133例患者进行问卷调查和斑贴试验（瑞典产“瑞敏牌”斑贴试剂）。结果：133例检测患者中有116例斑贴试验阳性，占受试者的87.22％，其中对1种阳性者42例（35.90％），对2种阳性者37例（31.62％），对3种阳性者19例（16.24％），对4种及4种以上阳性者19例（16.24％）。阳性发生率较高的前6位过敏原依次为甲醛、卡巴混合物、重铬酸钾、硫酸镍、硫酸汞、对苯类。阳性率与年龄、环境相关，与性别、化妆品的使用无关。结论：颜面再发性皮炎的发生与接触变应原关系密切，斑贴试验是指导颜面再发性皮炎治疗的一个有力手段。

关键词: 颜面再发性皮炎, 斑贴试验, 变应原, 甲醛, 接触性皮炎

Abstract: Objective: To explore the etiopathogenisis of facial recurrent dermatitis(FRD) by patch testing. Methods: 133 patients who had been clinically diagnosed facial recurrent dermatitis were studied by clinical questionnaire and patch testing.Results:The whole positive rate of patch testing is 87.22%(116 patients),The rate of positive reaction to one kind of kits is 35.90%(42 patients).To two kind of kits is31.62%(37 patients).To three is 16.24%(19 patients).To four and more than four is 16.24%(19 patients).The most 6 common contact allergens were formaldehyde, carba mix,ichromicum Kalium,niekel sulfate,mercury sulfate, paraben mix.The positive rate has relation with age and environment,but has no relation with sexual and cosmetics.Conclusions: Contacting allergen has a close connecting with FRD,so patch testing is a helpful method of directing us to therapy FRD.

Key words: Facial Recurrent Dermatitis, Patch Test, Allergen, Formaldehyde, Contact Dermatitis