中华皮肤科杂志 ›› 2023, Vol. 56 ›› Issue (6): 531-533.doi: 10.35541/cjd.20220584

• 论著 • 上一篇    下一篇

头癣致病病原菌单中心回顾性分析

郭艳阳    海璐明    朱振来    闫东    朱冠男    王刚    付萌   

  1. 空军军医大学西京皮肤医院,西安  710032
  • 收稿日期:2022-08-22 修回日期:2023-03-22 发布日期:2023-06-05
  • 通讯作者: 付萌 E-mail:fumeng@fmmu.edu.cn
  • 基金资助:
    国家自然科学基金(82173409)

Analysis of pathogenic fungi causing tinea capitis: a single-center retrospective study

Guo Yanyang, Hai Luming, Zhu Zhenlai, Yan Dong, Zhu Guannan, Wang Gang, Fu Meng   

  1. Department of Dermatology, Xijing Hospital, Air Force Medical University, Xi′an 710032, China
  • Received:2022-08-22 Revised:2023-03-22 Published:2023-06-05
  • Contact: Fu Meng E-mail:fumeng@fmmu.edu.cn
  • Supported by:
    National Natural Science Foundation of China (82173409)

摘要: 【摘要】 目的 了解本院近10年头癣患者的病原菌分布情况。方法 收集西京皮肤医院2011年1月至2020年12月门诊和病房收治的头癣患者871例,并回顾性分析患者的临床资料及病原菌分布情况,采用皮尔森卡方检验儿童和成人头癣病原菌分布的差异。结果 871例头癣患者中,男588例(67.5%),女283例(33.5%),其中< 1岁21例(2.40%)、1 ~ 3岁266例(30.50%)、4 ~ 6岁352例(40.40%)、7 ~ 12岁187例(21.50%)、12 ~ 18岁4例(0.50%)、18 ~ 74岁41例(4.70%)。共分离出致病菌株705株,其中犬小孢子菌599株(85.0%)、须癣毛癣菌复合体52株(7.4%)、断发毛癣菌27株(3.8%)、紫色毛癣菌18株(2.6%)。成人头癣病原菌中紫色毛癣菌比例(8.8%)显著高于儿童(2.2%),P = 0.048。结论 近10年西京皮肤医院收治的头癣感染者以1 ~ 6岁幼童为主,成人头癣较少。头癣的致病菌主要是犬小孢子菌,其次为须癣毛癣菌复合体。

关键词: 头癣, 病原菌, 犬小孢子菌, 须癣毛癣菌复合体, 儿童

Abstract: 【Abstract】 Objective To investigate the distribution of pathogenic fungi in patients with tinea capitis diagnosed in Xijing Hospital, Air Force Medical University in the past 10 years. Methods A total of 871 outpatients or inpatients with tinea capitis were collected from the Department of Dermatology, Xijing Hospital from January 2011 to December 2020, and their clinical data and pathogen distribution were retrospectively analyzed. Pearson chi-square test was used to analyze differences in the pathogen distribution between children and adult patients with tinea capitis. Results Of 871 patients with tinea capitis, 588 (67.5%) were males and 283 (33.5%) were females; 21 (2.40%) were aged less than 1 year, 266 (30.50%) aged 1 - 3 years, 352 (40.40%) aged 4 - 6 years, 187 (21.50%) aged 7 - 12 years, 4 (0.50%) aged 12 - 18 years, and 41 (4.70%) were aged 18 - 74 years. A total of 705 pathogenic strains were isolated from these patients, including 599 strains of Microsporum canis (85.0%), 52 strains of Trichophyton mentagrophytes complex (7.4%), 27 strains of Trichophyton tonsurans (3.8%), and 18 strains of Trichophyton violaceum (2.6%). Among the pathogenic fungi of tinea capitis, the proportion of Trichophyton violaceum was significantly higher in adults (8.8%) than in children (2.2%, P = 0.048). Conclusions In the past 10 years, the patients with tinea capitis in the Department of Dermatology, Xijing Hospital were mainly children aged 1 - 6 yearswhile adults, and adult patients with tinea capitis were uncommon. The main pathogen of tinea capitis was Microsporum canis, followed by Trichophyton mentagrophytes complex.

Key words: Tinea capitis, Pathogenic fungus, Microsporum canis, Trichophyton mentagrophytes complex, Children

引用本文

郭艳阳 海璐明 朱振来 闫东 朱冠男 王刚 付萌. 头癣致病病原菌单中心回顾性分析[J]. 中华皮肤科杂志, 2023,56(6):531-533. doi:10.35541/cjd.20220584

Guo Yanyang, Hai Luming, Zhu Zhenlai, Yan Dong, Zhu Guannan, Wang Gang, Fu Meng. Analysis of pathogenic fungi causing tinea capitis: a single-center retrospective study[J]. Chinese Journal of Dermatology, 2023, 56(6): 531-533.doi:10.35541/cjd.20220584