中华皮肤科杂志

• 论著 • 上一篇    下一篇

强脉冲光治疗雀斑、咖啡斑、脂溢性角化病的疗效观察

刘梅, 李远宏, 吴严, 张丽, 高兴华, 何春涤, 陈洪铎   

  1. 中国医科大学附属第一医院皮肤性病科, 沈阳, 110001
  • 收稿日期:2006-08-21 出版日期:2007-06-15 发布日期:2007-06-15
  • 通讯作者: 陈洪铎,email:chenhd@cae.cn E-mail:chenhd@cae.cn

Efficacy of intense pulsed light on freckles, café-au-lait spots and seborrheic keratoses

LIU Mei, LI Yuan-hong, WU Yan, ZHANG Li, GAO Xing-Hua, HE Chun-di, CHEN Hong-Duo   

  1. Department of Dermatology, NO.1 Hospital of China Medical University, Shenyang 110001, China
  • Received:2006-08-21 Online:2007-06-15 Published:2007-06-15

PDF (PC)

163

赞

摘要： 目的 探讨强脉冲光治疗雀斑、咖啡斑和脂溢性角化病的疗效。方法 强脉冲光治疗仪治疗199例患者,其中雀斑69例,咖啡斑58例,伴有明显色素沉着的脂溢性角化病72例。每3周治疗1次,4次为1疗程。每次治疗前采集皮损图像以评估治疗效果。采用5级分类法来统计改善率情况。同时评定医生和患者的主观满意程度。结果 雀斑疗效显著,治疗2次后全部患者的改善率达到50%～100%。咖啡斑、脂溢性角化病疗效也显著,治疗4次后有80%以上的患者改善率达到50%～100%。对以上三种疾病的疗效,医生满意率96.73%,患者满意率94.65%,二者差异无统计学意义(x2=0.13,P>0.05)。结论 应用强脉冲光治疗雀斑、咖啡斑、脂溢性角化病的近期疗效好,不良反应小。

关键词: 雀斑, 咖啡斑, 角化病, 脂溢性, 强脉冲光

Abstract: Objective To observe the efficacy of intense pulsed light(IPL)on freckles,café-au-lait spots and seborrheic keratoses.Methods A total of 199 patients were treated,including 69 cases of freckle, 58 cases of café-au-lait spot and 72 cases of seborrheic keratosis.All patients were treated with IPL every 3 weeks for 12 weeks.Before each session,lesions were photographed,and therapeutic effects were evaluated by physicians based on improvement in pigmentation and lesion area recorded on the photoes.The improvement rate was classified into five grades(unchange,0%～25%,26%～50%,51%～75%,76%～100%).In addition,subjective satisfaction of physicians and patients was recorded.Results Patients with freckles responsed remarkably,and more than 50% improvement was obtained in 55% and 100% patients after the first and second session,respectively.Patients with café-au-lait spots or seborrheic keratoses also responsed well,and more than 80% patients experienced 50%～100% improvement after the fourth session.The satisfaction rates of the physicians and patients were 96.73% and 94.65%,respectively, showing no statistical difference between them(x2=0.13,P>0.05).Conclusions IPL is a new modality for the treatment of freckles,café-au-lait spots and seborrheic keratoses,with good short-term effect and few adverse effects.

Key words: Keratosis, Freckles, Café-au-lait spots, seborrheic, Intense pulsed light