中华皮肤科杂志 ›› 2021, Vol. 54 ›› Issue (5): 382-390.doi: 10.35541/cjd.20200796

• 指南与共识 • 上一篇    下一篇

[开放获取]    甲氨蝶呤治疗免疫相关性皮肤病专家共识

中国医师协会皮肤科医师分会自身免疫病专业委员会   

  1. 中国医师协会皮肤科医师分会自身免疫病专业委员会
  • 收稿日期:2020-08-10 修回日期:2021-02-22 发布日期:2021-04-29
  • 通讯作者: 刘晓明 E-mail:liuxm@hku-szh.org

Expert consensus on methotrexate in the treatment of immune-associated dermatoses

Committee on Autoimmune Diseases, China Dermatologist Association   

  1. Committee on Autoimmune Diseases, China Dermatologist Association
  • Received:2020-08-10 Revised:2021-02-22 Published:2021-04-29
  • Contact: Liu Xiaoming E-mail:liuxm@hku-szh.org

摘要: 【摘要】 甲氨蝶呤是治疗免疫相关性皮肤病的常用药物。为规范甲氨蝶呤在免疫相关性皮肤病治疗中的应用,中国医师协会皮肤科医师分会自身免疫病专业委员会以国内外甲氨蝶呤的研究成果为基础,组织国内皮肤病专家共同讨论制定了本共识。主要内容包括甲氨蝶呤的作用机制,在银屑病、结缔组织病、自身免疫性大疱病、血管炎及皮肤T细胞淋巴瘤的治疗应用,不良反应及使用中注意事项,以及甲氨蝶呤在特殊人群的应用。

关键词: 甲氨蝶呤, 皮肤疾病, 银屑病, 结缔组织疾病, 皮肤疾病, 水疱大疱性, 淋巴瘤, T细胞, 皮肤, 血管炎, 专家共识

Abstract: 【Abstract】 Methotrexate is commonly used in the treatment of immune-associated dermatoses. In order to standardize the use of methotrexate in the treatment of immune-associated dermatoses, the Committee on Autoimmune Diseases, China Dermatologist Association organized Chinese dermatologists to discuss and develop this consensus based on domestic and international research findings. This consensus summarizes the mechanism of action of methotrexate, its application in the treatment of psoriasis, connective tissue diseases, autoimmune bullous diseases, vasculitis and cutaneous T-cell lymphoma, adverse reactions and considerations during its use, as well as its application in special populations.

Key words: Methotrexate, Skin diseases, Psoriasis, Connective tissue diseases, Skin diseases, vesiculobullous, Lymphoma, T-cell, cutaneous, Vasculitis, Consensus statement

引用本文

中国医师协会皮肤科医师分会自身免疫病专业委员会. [开放获取]    甲氨蝶呤治疗免疫相关性皮肤病专家共识[J]. 中华皮肤科杂志, 2021,54(5):382-390. doi:10.35541/cjd.20200796

Committee on Autoimmune Diseases, China Dermatologist Association. Expert consensus on methotrexate in the treatment of immune-associated dermatoses[J]. Chinese Journal of Dermatology, 2021, 54(5): 382-390.doi:10.35541/cjd.20200796