中华皮肤科杂志 ›› 2011, Vol. 44 ›› Issue (8): 586-589.

• 研究报道 • 上一篇    下一篇

化妆品变应性接触性皮炎变应原检测分析

蔡永莲1,刘润秋2,施辛3,张静1,黎平1   

  1. 1. 苏州大学附属第二医院
    2. 盐城市第一人民医院皮肤科
    3. 苏州大学附属第二医院皮肤科
  • 收稿日期:2010-09-28 修回日期:2011-03-06 出版日期:2011-08-15 发布日期:2011-07-26
  • 通讯作者: 施辛 E-mail:shx9@163.com

Detection of causative allergens of cosmetic allergic contact dermatitis

Yonglian Cai1,liu runqiu2, Jing Zhang1,Ping Li1   

  • Received:2010-09-28 Revised:2011-03-06 Online:2011-08-15 Published:2011-07-26

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摘要：

目的 调查化妆品变应原种类，为化妆品过敏提供流行病学资料和临床依据。方法 对89例门诊疑诊化妆品变应性接触性皮炎患者采用49种欧洲化妆品系列变应原及5种中国筛查系列化妆品变应原进行斑贴试验，按国际接触性皮炎研究组推荐标准判读结果。 结果 89例患者中，61例对1种或1种以上化妆品变应原过敏，阳性反应率68.5%。其中阳性率较高的有香料33.7%，防腐剂30.3%，对苯二胺25.8%，阿莫醇10.1%。结论 香料、防腐剂、对苯二胺、阿莫醇等是化妆品变应性接触性皮炎患者的主要致敏原。

关键词: 斑贴试验

Abstract:

Objective To make a survey on common cosmetic allergens, and to provide epidemiological data and clinical evidence for cosmetic allergy. Methods Patch test was performed by using 49 cosmetic allergens from a European cosmetic series and 5 Chinese standard screening allergens on 89 patients with suspected cosmetic allergic contact dermatitis. Test results were determined according to the International Contact Dermatitis Research Group （ICDRG） recommendation. Results Of the 89 patients, 61 （68.5%） showed positive reactions to one or more cosmetic allergens. The most common allergens were fragrances （33.7%）, followed by preservatives （30.3%）, para-phenylenediamine （25.8%） and amerchol L 101（10.1%）. Conclusion Fragrances, preservatives, para-phenylenediamine and amerchol L 101 are dominant causative allergens in patients with cosmetic allergic contact dermatitis.

Key words: Patch test