中华皮肤科杂志 ›› 2011, Vol. 44 ›› Issue (7): 527-527.

• 病例报告 • 上一篇    下一篇

面部多发性毛发平滑肌瘤一例

赵一栋1,宋琳毅2,杨之蕙3,丘佳明3   

  1. 1. 常熟第二人民医院皮肤科
    2. 苏州大学附属第一医院
    3.
  • 收稿日期:2010-08-20 修回日期:2010-12-20 出版日期:2011-07-15 发布日期:2011-07-12
  • 通讯作者: 赵一栋 E-mail:doctbeyond@sina.com

Multiple pilary leiomyoma on the face: a case report

  • Received:2010-08-20 Revised:2010-12-20 Online:2011-07-15 Published:2011-07-12

摘要:

【摘要】 报告1例面部多发性毛发平滑肌瘤。患者男,43岁,右侧面部及额头部红色斑丘疹,伴冬季疼痛20年余,近4年加重。临床表现为粟粒至黄豆大小,高出皮面的丘疹和结节分布于右侧面颊部以及额部右侧,呈淡红色至红色,簇集状,质地坚实,基底稍呈浸润状。冰块实验阳性。患者无其他系统疾病。皮损组织病理检查:表皮大致正常,真皮内见肿瘤细胞不规则聚集或交织成束,肿瘤细胞细长,胞浆嗜酸,胞核两端钝圆或呈雪茄样,免疫组化显示平滑肌强阳性的特征:Desmin和SMA(+),结合临床诊断多发性毛发平滑肌瘤。由于该患者皮损面积大,未能手术切除,随访。

关键词: 多发性

Abstract:

【Abstract】 We are reporting a 43-year-old male with Multiple leiomyoma on his face. He had suffered from maculopapules on his right face and forehead for more than 20 years, with pains in winter seasons. The symptoms had become severer for last 4 years. It was observed from the clinical manifestations that papules had the size of from soybean to millet. These papules and nodules protruding from the facial surface were distributed around his right cheek and right forehead, colored from pink to red, with a characteristic of aggregations, solid texture, slight infiltration at their basements. The ice lab test showed positive although the patient historically had no other systematically illness. The histological examination on skin lesions indicated that the epidermis was basically normal, there existed tumor cells in the forms of irregular aggregations or interlacing bundles within the dermis. These cells were slender, and were of the characteristic of eosinophilic cytoplasm. Both ends of nucleus showed obtusely circular or cigar-like shape. The immunohistochemistry illustrated strongly positive feature for smooth muscle: Desmin and SMA(+). Combined with clinical diagnosis, it was thus concluded that the patient’s suffering from the multiple facial leiomyoma. Since the patient’s skin damage has extended to a larger area, a surgical excision was not an ideal option and the follow-up visits were proposed.

Key words: Multiple