中华皮肤科杂志 ›› 2010, Vol. 43 ›› Issue (2): 105-107.

• 论著 • 上一篇    下一篇

点阵式Er：YAG激光治疗痤疮瘢痕及毛孔粗大的疗效观察

吴严1,李远宏1,祝霞1,贾丽丽1,徐天华1,张丽1,徐宏慧2,陈洪铎3   

  1. 1. 沈阳 中国医科大学附属第一医院皮肤科
    2. 中国医科大学第一临床医院皮肤科 110001
    3. 中国医科大学第一附属医院皮肤科
  • 收稿日期:2009-04-22 修回日期:2009-07-07 出版日期:2010-02-15 发布日期:2012-03-30
  • 通讯作者: 吴严 E-mail:jlwuyan@126.com
  • 基金资助:
    2007年教育部创新团队基金;2007年教育部创新团队基金

Efficacy of ablative fractionated Er:YAG laser in facial acne scars and enlarged pores

  • Received:2009-04-22 Revised:2009-07-07 Online:2010-02-15 Published:2012-03-30

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摘要： 目的 探讨点阵式掺铒钇铝石榴石（Er:YAG）激光对于面部凹陷性痤疮瘢痕及毛孔粗大的疗效。方法 轻至中度凹陷性痤疮瘢痕41例，予中长脉宽、能量800 ～ 1200 mJ、定点连续发射4 ～ 8个脉冲。毛孔粗大23例，予中脉宽、能量800 ～ 1000 mJ、定点连续发射2 ～ 4个脉冲。疗程为3 ～ 5次，每次间隔1个月。由医生对治疗后皮损改善程度进行评价，由患者对疗效进行满意度评价。应用三维皮肤成像仪获取皮肤立体图像，评价治疗对皮肤粗糙度的影响。结果 医生评估痤疮瘢痕患者皮损改善程度为82.93%，毛孔粗大患者皮损改善程度为86.96%；两种皮损患者满意率分别为88.80%和91.30%；与治疗前相比，治疗后表示粗糙度的Ra值及Rz值分别下降18.74%和21.01%（P < 0.001）。结论 点阵式Er:YAG激光可有效改善面部轻中度凹陷性痤疮瘢痕及毛孔粗大。

关键词: 痤疮，寻常, 点阵式Er:YAG激光, 瘢痕

Abstract: Objective To investigate the efficacy of ablative fractionated erbium: yttrium aluminum garnet （Er: YAG） laser in facial acne scars and enlarged pores. Methods Forty-one patients with mild to moderate pitted acne scars and 23 patients with enlarged pores were treated with 81 （9 × 9） bits of facula for 3 to 5 sessions at an interval of 1 month. For acne scars, the pulse duration was medium to long, energy at 800 to 1200 mJ, and number of stacking passes 4 to 8; for enlarged pores, the pulse duration was medium, energy at 800 to 1000 mJ and number of stacking passes 2 to 4. The clinical improvement was evaluated by 2 blinded dermatologists. Meanwhile, the satisfaction rate was self-assessed by patients. Three-dimensional （3D） microtopography imaging system was used to evaluate the improvement in surface roughness. Results The efficacy reached 82.93% and 86.96% for acne scars and enlarged pores, respectively. The satisfaction rate was 88.80% and 91.30% in patients with acne scars and those with enlarged pores, respectively. After treatment, the Ra and Rz values, as the indicators of roughness, decreased by 18.74% and 21.01%, individually （P < 0.001） in 11 patients including 6 with acne scars and 5 with enlarged pores. Conclusion Ablative fractionated Er:YAG laser can efficiently resurface pitted acne scars and shrink enlarged pores.

Key words: ablative fractionated Er:YAG laser, scar