中华皮肤科杂志 ›› 2009, Vol. 42 ›› Issue (2): 88-90.

• 论著 • 上一篇    下一篇

长脉冲可调脉宽Nd:YAG激光治疗毛细血管瘤124例

姚蕾 钟淑霞 李珊山 田亚平 刘鹤松 于艳 徐亚娟   

  1. 吉林大学第一医院皮肤科 长春市吉林大学第一医院皮肤科 长春市吉林大学第一医院皮肤科 长春市吉林大学第一医院皮肤科 长春市白求恩医科大学第一临床学院
  • 收稿日期:2008-07-14 修回日期:2008-08-22 出版日期:2009-02-15 发布日期:2009-02-15
  • 通讯作者: 姚蕾 E-mail:yaolei_2008@163.com

Therapeutic efficacy of long-pulsed tunable Nd:YAG laser on capillary hemangioma

  • Received:2008-07-14 Revised:2008-08-22 Online:2009-02-15 Published:2009-02-15

摘要:

目的 探讨长脉冲可调脉宽Nd:YAG激光治疗毛细血管瘤的疗效及影响因素。方法 长脉冲可调脉宽Nd:YAG激光治疗毛细血管瘤患者124例,根据皮损面积、颜色、深浅选择参数,并根据即刻反应调整参数。治疗间隔1个月。结果 135个皮损的治愈率为74.07%,有效率为90.37%。各因素对疗效的影响:皮损面积越小,有效率越高(P < 0.01),部位及皮损厚度的不同对疗效无影响(均为P > 0.05)。不良反应:术后水疱发生率为8.89%,萎缩性瘢痕发生率为2.96%。结论 长脉冲可调脉宽Nd:YAG激光治疗毛细血管瘤效果好,不良反应小,是治疗毛细血管瘤的有效方法之一。

关键词: Nd:YAG激光;血管瘤;治疗

Abstract:

Objective To evaluate the efficacy of long-pulsed tunable Nd: YAG laser on capillary hemangioma and to analyse its influencial factors. Methods A retrospective review was conducted on 124 patients with 135 vascular lesions treated with long-pulsed tunable Nd:YAG laser from February, 2007 to January, 2008. Working parameters, including spot size (3 - 5 mm), pulse duration (10 - 30 ms) and fluence (120 - 200 J/cm2) were determined based on the size, color and depth of lesions and adjusted according to the immediate reaction of lesions. The interval of two treatments was 1 month. Results Of the 135 lesions, 100 experienced a more than 95% subsidence, 22 achieved 60% - 94% subsidence, 11 got 30% - 59% subsidence, and 2 reached less than 30% subsidence. The cure rate and effective rate were 74.07% and 90.37% respectively. Smaller lesions showed a better response to the treatment than larger ones (P < 0.0001), whereas the sites and depth of lesions had no effect on the efficacy (both P > 0.05). Atrophy scar occurred in 4 (2.96%) lesions, and blisters in 12 (8.89%) lesions after the treatment. No purpura or pigmentary changes occurred. Conclusion The long-pulsed tunable Nd:YAG laser is an effective treatment for capillary hemangioma with fast action and few side reactions.

Key words: Nd:YAG laser;Hemangioma;Therapeutic efficacy